STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR2C2Nuclear receptor subfamily 2 group C member 2. (629 aa)    
Predicted Functional Partners:
JAZF1
JAZF zinc finger 1.
   
 
 0.891
NCOR1
Nuclear receptor corepressor 1.
   
 0.687
DCLRE1B
DNA cross-link repair 1B.
   
 
 0.668
ZNF827
Zinc finger protein 827.
   
 
 0.656
NCOR2
Nuclear receptor corepressor 2.
   
 0.636
SRBD1
S1 RNA binding domain 1.
   
 
 0.605
ZBTB48
Zinc finger and BTB domain containing 48.
    
 
 0.600
ZNF276
Zinc finger protein 276.
   
 
 0.581
PCBP3
Poly(rC) binding protein 3.
    
 
 0.572
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.556
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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