Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GIMAP8GTPase, IMAP family member 8. (628 aa)    
Predicted Functional Partners:
GIMAP4
GTPase, IMAP family member 4.
  
  
0.882
GIMAP1
GTPase, IMAP family member 1.
   
  
 0.848
F1PVT5_CANLF
AIG1-type G domain-containing protein.
  
  
0.835
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
 
 0.833
SEL1L3
SEL1L family member 3.
    
 
 0.726
LEXM
Lymphocyte expansion molecule.
   
 
 0.719
ZNF385C
Zinc finger protein 385C.
    
 0.717
DNAJC14
J domain-containing protein.
    
 
 0.687
P2RY13
Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.668
PSMD3
Proteasome 26S subunit, non-ATPase 3.
    
 
 0.635
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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