STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOE1Target of EGR1, exonuclease. (510 aa)    
Predicted Functional Partners:
SNUPN
Snurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family.
    
 
 0.932
MUTYH
MutY DNA glycosylase.
      
 0.884
PRCC
Proline rich mitotic checkpoint control factor.
   
   0.777
SNX14
Sorting nexin 14.
      
 0.777
SNRPA1
Small nuclear ribonucleoprotein polypeptide A.
    
 
 0.767
ENSCAFP00000051873
Uncharacterized protein.
    
 
 0.767
GEMIN8
Gem nuclear organelle associated protein 8.
      
 0.766
SF3B3
Splicing factor 3b subunit 3.
    
   0.735
GEMIN4
Gem nuclear organelle associated protein 4.
   
  
 0.697
GEMIN2
Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.
      
 0.684
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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