STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC122Coiled-coil domain containing 122. (291 aa)    
Predicted Functional Partners:
LACC1
Uncharacterized protein.
   
  
 0.795
CCDC88B
Non-specific serine/threonine protein kinase.
      
 0.719
IL18RAP
Interleukin 18 receptor accessory protein.
      
 0.593
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
      
 0.553
TNFSF15
TNF superfamily member 15.
   
  
 0.553
MTAP
Methylthioadenosine phosphorylase.
   
  
 0.483
GLT6D1
Glycosyltransferase 6 domain containing 1.
   
  
 0.474
MTMR7
Myotubularin related protein 7.
   
  
 0.435
IL1RL1
Interleukin 1 receptor like 1.
      
 0.414
NOD2
Uncharacterized protein.
      
 0.406
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.