STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPDL4-hydroxyphenylpyruvate dioxygenase. (399 aa)    
Predicted Functional Partners:
HGD
Homogentisate 1,2-dioxygenase.
 
 0.978
FAH
Fumarylacetoacetase.
 
  
 0.933
TAT
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.919
MCEE
Methylmalonyl-CoA epimerase.
  
 
 0.817
GLOD5
Glyoxalase domain-containing protein 5; Belongs to the glyoxalase I family.
      
 0.817
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
  
 
 0.792
PCCB
Propionyl-CoA carboxylase subunit beta.
  
 
 0.792
GOT1
Aspartate aminotransferase.
  
 
 0.744
GOT2
Aspartate aminotransferase.
  
 
 0.685
AADAT
Aminoadipate aminotransferase.
  
 
 0.683
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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