STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN2Nectin cell adhesion molecule 2. (541 aa)    
Predicted Functional Partners:
CD226
CD226 molecule.
    
 0.999
NECTIN3
Nectin cell adhesion molecule 3.
   
0.998
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
    
 0.994
AFDN
Afadin, adherens junction formation factor.
    
 0.994
NECTIN1
Uncharacterized protein.
   
0.957
CRTAM
Cytotoxic and regulatory T cell molecule.
     
 0.907
NECTIN4
Nectin cell adhesion molecule 4.
    
0.886
PARD3
Par-3 family cell polarity regulator.
     
  0.881
PVRIG
PVR related immunoglobulin domain containing.
    
 
 0.865
TMEM62
Transmembrane protein 62.
      
 0.801
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.