STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN2Nectin cell adhesion molecule 2. (541 aa)    
Predicted Functional Partners:
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
    
 0.997
AFDN
Afadin, adherens junction formation factor.
    
 0.979
NECTIN3
Nectin cell adhesion molecule 3.
    
0.971
CD226
CD226 molecule.
    
 0.968
NECTIN1
Uncharacterized protein.
    
0.944
CRTAM
Cytotoxic and regulatory T cell molecule.
     
 0.905
NECTIN4
Nectin cell adhesion molecule 4.
    
0.904
PARD3
Par-3 family cell polarity regulator.
    
  0.901
VSIR
V-set immunoregulatory receptor.
      
 0.737
LOC100683099
MHC_I_2 domain-containing protein.
      
 0.623
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.