STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXND1Plexin D1. (1928 aa)    
Predicted Functional Partners:
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
    
 0.999
SEMA4A
Semaphorin 4A; Belongs to the semaphorin family.
    
 0.971
SEMA3C
Semaphorin 3C; Belongs to the semaphorin family.
    
 
 0.871
SEMA4C
Semaphorin 4C; Belongs to the semaphorin family.
   
 
0.826
SEMA3D
Semaphorin 3D; Belongs to the semaphorin family.
   
 
 0.808
NRP2
Neuropilin; Belongs to the neuropilin family.
   
 
 0.783
NRP1
Neuropilin 1.
   
 
 0.779
SEMA3B
Semaphorin 3B; Belongs to the semaphorin family.
    
 
 0.753
SEMA3G
Semaphorin 3G; Belongs to the semaphorin family.
    
 
 0.726
SEMA4D
Semaphorin 4D; Belongs to the semaphorin family.
    
 
 0.694
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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