STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRCPProlylcarboxypeptidase. (518 aa)    
Predicted Functional Partners:
MEP1A
Meprin A subunit.
     
 0.984
MME
Uncharacterized protein.
   
 
 0.967
MEP1B
Meprin A subunit.
     
 0.944
ACE2
Angiotensin-converting enzyme.
     
 0.933
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
     
 0.923
CMA1
Chymase; Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
   
 
 0.909
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
     
 0.900
CTSG
Granzyme B; Belongs to the peptidase S1 family.
   
 
 0.889
ACE
Angiotensin-converting enzyme.
     
 0.861
PREP
Prolyl endopeptidase.
      
 0.849
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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