STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBLCCbl proto-oncogene C. (497 aa)    
Predicted Functional Partners:
EGFR
Receptor protein-tyrosine kinase.
   
 0.992
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.929
FGFR4
Fibroblast growth factor receptor.
    
  0.895
CBLB
Cbl proto-oncogene B.
    
  0.893
CBL
Cbl proto-oncogene.
    
  0.888
SH3GLB2
SH3 domain containing GRB2 like, endophilin B2.
    
  0.885
SH3GLB1
SH3 domain containing GRB2 like, endophilin B1.
    
  0.885
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
    
  0.884
SH3GL1
SH3 domain containing GRB2 like 1, endophilin A2.
    
  0.884
MST1R
Macrophage stimulating 1 receptor.
   
 0.879
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.