STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOC1Amine oxidase. (774 aa)    
Predicted Functional Partners:
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).
   
 
 0.960
MAOB
Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).
   
 
 0.960
HNMT
Histamine N-methyltransferase.
     
 0.957
HDC
Histidine decarboxylase.
     
 0.957
AGMAT
Agmatinase; Belongs to the arginase family.
   
 
 0.954
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 
 0.943
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
     
 0.943
ALDH1B1
Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family.
   
 0.936
MAPKAPK5
MAPK activated protein kinase 5; Belongs to the aldehyde dehydrogenase family.
   
 0.936
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
   
 0.935
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.