STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOC1Amine oxidase. (774 aa)    
Predicted Functional Partners:
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
     
 0.955
MAOB
Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).
   
 
 0.938
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).
   
 
 0.937
HDC
Histidine decarboxylase.
     
 0.934
DDC
Dopa decarboxylase.
     
 0.933
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 
 0.930
ALDH3A2
Multidrug and toxin extrusion protein; Belongs to the aldehyde dehydrogenase family.
   
 0.908
HNMT
Histamine N-methyltransferase.
     
 0.906
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
   
 0.896
ALDH9A1
Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family.
   
 0.896
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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