STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTOP3Otopetrin 3. (571 aa)    
Predicted Functional Partners:
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
      
 0.567
C4BPB
Complement component 4 binding protein beta.
      
 0.567
RGR
Retinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
      
 0.542
RNF186
Ring finger protein 186.
      
 0.528
ALX1
ALX homeobox 1.
      
 0.526
TMEM128
Transmembrane protein 128.
      
 0.523
CCL28
C-C motif chemokine 28; Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner (By similarity); Belongs to the intercrine beta (chemokine CC) family.
      
 0.523
DRD5
Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.
      
 0.522
NR2C1
Nuclear receptor subfamily 2 group C member 1.
      
 0.476
GUCA2A
Guanylate cyclase activator 2A.
      
 0.466
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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