STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD3HECT domain E3 ubiquitin protein ligase 3. (861 aa)    
Predicted Functional Partners:
PGM2
Phosphoglucomutase 2.
   
    0.805
KIAA2013
KIAA2013.
   
  
 0.674
DHRS7
Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.575
GSS
Glutathione synthetase.
      
 0.538
PLS1
Plastin 1.
   
 
 0.533
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.523
ENSCAFP00000054759
Ubiquitin-like domain-containing protein.
   
 
 0.523
ENSCAFP00000061156
Ubiquitin-like domain-containing protein.
   
 
 0.523
RNF220
Ring finger protein 220.
   
 
 0.505
MTDH
Metadherin.
    
 
 0.504
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.