STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PREBProlactin regulatory element binding. (418 aa)    
Predicted Functional Partners:
SAR1A
Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.
   
 0.978
SAR1B
Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.
   
 0.978
MIA2
SH3 domain-containing protein.
    
 0.949
SEC24B
SEC24 homolog B, COPII coat complex component.
   
 
 0.768
SEC24C
SEC24 homolog C, COPII coat complex component.
   
 0.753
SEC23A
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 0.727
STX5
Syntaxin 5; Belongs to the syntaxin family.
   
 
 0.712
SEC24A
SEC24 homolog A, COPII coat complex component.
   
 
 0.701
SEC24D
SEC24 homolog D, COPII coat complex component.
   
 0.700
LMAN1
Lectin, mannose binding 1.
   
 0.679
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.