STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD6IPProgrammed cell death 6 interacting protein. (874 aa)    
Predicted Functional Partners:
CHMP4B
Charged multivesicular body protein 4B.
   
 0.977
CHMP4C
Charged multivesicular body protein 4C.
   
 0.977
CHMP4A
Charged multivesicular body protein 4A.
    
 0.973
CEP55
Centrosomal protein 55.
    
 
 0.964
MDP1
Uncharacterized protein.
    
 0.948
TSG101
Tumor susceptibility 101.
   
 
 0.934
EGFR
Receptor protein-tyrosine kinase.
    
 
 0.930
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 
 0.930
MVB12B
Multivesicular body subunit 12B.
     
 0.925
MVB12A
Multivesicular body subunit 12A.
   
 
 0.912
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.