STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD6IPProgrammed cell death 6 interacting protein. (874 aa)    
Predicted Functional Partners:
CHMP4B
Charged multivesicular body protein 4B.
   
 0.987
CHMP4C
Charged multivesicular body protein 4C.
   
 0.987
MVB12A
Multivesicular body subunit 12A.
   
 
 0.946
MVB12B
Multivesicular body subunit 12B.
     
 0.923
TSG101
Tumor susceptibility 101.
   
 
 0.887
VPS4A
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 
 0.841
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 
 0.830
ENSCAFP00000045211
SB domain-containing protein.
   
 
 0.820
VTA1
Vesicle trafficking 1.
   
  
 0.773
PDCD6
Programmed cell death 6.
   
 
 0.758
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.