STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK3Serine/threonine-protein kinase PLK. (768 aa)    
Predicted Functional Partners:
CDC25C
Cell division cycle 25C.
   
 0.914
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
0.904
CD209
C-type lectin domain-containing protein.
   
  0.901
LSP1
Lymphocyte specific protein 1.
   
 
 0.831
KSR1
Kinase suppressor of ras 1.
    
0.830
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.823
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.736
PPP4C
Serine/threonine-protein phosphatase.
   
 
 0.699
RAD21
RAD21 cohesin complex component.
   
 
 0.679
RAD21L1
RAD21 cohesin complex component like 1.
   
 
 0.677
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.