STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYPD3LY6/PLAUR domain containing 3. (348 aa)    
Predicted Functional Partners:
PHLDB3
Pleckstrin homology like domain family B member 3.
   
  
 0.831
ZNF575
Zinc finger protein 575.
   
  
 0.817
TBRG4
Transforming growth factor beta regulator 4.
    
 
 0.656
CD177
CD177 molecule.
      
 0.653
TEX101
Testis expressed 101.
   
  
 0.625
CYP4X1
Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family.
      
 0.618
GPR87
G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.617
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
   
  
 0.589
OSGIN1
Oxidative stress induced growth inhibitor 1.
    
 
 0.573
STXBP2
Syntaxin-binding protein 2; Involved in the protein trafficking from the Golgi apparatus to the plasma membrane; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.