STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD177CD177 molecule. (408 aa)    
Predicted Functional Partners:
PECAM1
Platelet and endothelial cell adhesion molecule 1.
    
 0.928
ELANE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
 0.815
B9D2
Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]
      
 0.710
CBS
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.692
CEACAM18
Carcinoembryonic antigen related cell adhesion molecule 18.
      
 0.670
PHLDB3
Pleckstrin homology like domain family B member 3.
      
 0.647
ZNF575
Zinc finger protein 575.
      
 0.629
LYPD3
LY6/PLAUR domain containing 3.
      
 0.582
BCL3
BCL3 transcription coactivator.
   
  
 0.580
CEACAM16
Uncharacterized protein.
   
  
 0.580
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.