GAB2 protein (Canis lupus familiaris) - STRING interaction network

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Score

GAB2

GRB2 associated binding protein 2. (663 aa)

Predicted Functional Partners:

GRB2

0.929

PTPN11

0.903

LOC100683481

0.903

LYN

0.903

PIK3CB

0.894

PDGFRB

0.890

SOS1

0.890

SOS2

0.890

PIK3R1

0.889

PLCG2

0.889

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAB2	GRB2	ENSCAFP00000007132	ENSCAFP00000049390	GRB2 associated binding protein 2.	Growth factor receptor bound protein 2.	0.929
GAB2	LOC100683481	ENSCAFP00000007132	ENSCAFP00000045355	GRB2 associated binding protein 2.	Tyrosine-protein phosphatase domain-containing protein.	0.903
GAB2	LYN	ENSCAFP00000007132	ENSCAFP00000046785	GRB2 associated binding protein 2.	Tyrosine-protein kinase.	0.903
GAB2	PDGFRB	ENSCAFP00000007132	ENSCAFP00000000714	GRB2 associated binding protein 2.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at v [...]	0.890
GAB2	PIK3CB	ENSCAFP00000007132	ENSCAFP00000011245	GRB2 associated binding protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.894
GAB2	PIK3R1	ENSCAFP00000007132	ENSCAFP00000011322	GRB2 associated binding protein 2.	Phosphoinositide-3-kinase regulatory subunit 1.	0.889
GAB2	PLCG2	ENSCAFP00000007132	ENSCAFP00000029622	GRB2 associated binding protein 2.	Phosphoinositide phospholipase C.	0.889
GAB2	PTPN11	ENSCAFP00000007132	ENSCAFP00000013074	GRB2 associated binding protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.903
GAB2	SOS1	ENSCAFP00000007132	ENSCAFP00000009512	GRB2 associated binding protein 2.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.890
GAB2	SOS2	ENSCAFP00000007132	ENSCAFP00000021080	GRB2 associated binding protein 2.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.890
GRB2	GAB2	ENSCAFP00000049390	ENSCAFP00000007132	Growth factor receptor bound protein 2.	GRB2 associated binding protein 2.	0.929
GRB2	LOC100683481	ENSCAFP00000049390	ENSCAFP00000045355	Growth factor receptor bound protein 2.	Tyrosine-protein phosphatase domain-containing protein.	0.984
GRB2	LYN	ENSCAFP00000049390	ENSCAFP00000046785	Growth factor receptor bound protein 2.	Tyrosine-protein kinase.	0.739
GRB2	PDGFRB	ENSCAFP00000049390	ENSCAFP00000000714	Growth factor receptor bound protein 2.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at v [...]	0.984
GRB2	PIK3CB	ENSCAFP00000049390	ENSCAFP00000011245	Growth factor receptor bound protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.846
GRB2	PIK3R1	ENSCAFP00000049390	ENSCAFP00000011322	Growth factor receptor bound protein 2.	Phosphoinositide-3-kinase regulatory subunit 1.	0.971
GRB2	PLCG2	ENSCAFP00000049390	ENSCAFP00000029622	Growth factor receptor bound protein 2.	Phosphoinositide phospholipase C.	0.884
GRB2	PTPN11	ENSCAFP00000049390	ENSCAFP00000013074	Growth factor receptor bound protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.996
GRB2	SOS1	ENSCAFP00000049390	ENSCAFP00000009512	Growth factor receptor bound protein 2.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.999
GRB2	SOS2	ENSCAFP00000049390	ENSCAFP00000021080	Growth factor receptor bound protein 2.	SOS Ras/Rho guanine nucleotide exchange factor 2.	0.999