STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUGT1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (333 aa)    
Predicted Functional Partners:
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
   
 0.982
NOD1
Nucleotide binding oligomerization domain containing 1.
    
 0.974
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 
 0.909
NLRP3
NLR family pyrin domain containing 3.
    
 0.903
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
   
 0.885
ENSCAFP00000061869
Uncharacterized protein.
   
 0.885
NOD2
Uncharacterized protein.
    
 0.882
ITGB1BP2
Integrin subunit beta 1 binding protein 2.
   
 0.873
CHORDC1
Cysteine and histidine rich domain containing 1.
   
 0.873
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity). Has ATPase activity. Belongs to the heat shock protein 90 family.
   
 0.848
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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