STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNMDChondromodulin. (305 aa)    
Predicted Functional Partners:
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.635
PGAM2
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
      
 0.577
MATN3
Matrilin 3.
   
 
 0.522
ECPAS
Ecm29 proteasome adaptor and scaffold.
      
 0.485
COL9A3
Collagen type IX alpha 3 chain.
   
  
 0.465
COL2A1
Collagen type II alpha 1 chain.
   
  
 0.438
TMEM100
Transmembrane protein 100.
  
     0.433
ECRG4
ECRG4 augurin precursor.
      
 0.426
RHPN1
Rhophilin Rho GTPase binding protein 1.
   
  
 0.414
ACAN
Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
  
 0.410
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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