THRSP protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

THRSP

Thyroid hormone responsive. (149 aa)

Predicted Functional Partners:

MID1IP1

0.916

FASN

0.830

ELOVL6

0.668

PCK1

0.606

PCCA

0.592

SYT3

0.576

ZNF613

0.574

CTU1

0.573

C21H11orf58

0.570

PLIN1

0.562

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C21H11orf58	THRSP	ENSCAFP00000038757	ENSCAFP00000007232	SMAP domain-containing protein.	Thyroid hormone responsive.	0.570
CTU1	SYT3	ENSCAFP00000004252	ENSCAFP00000004392	ATP_bind_3 domain-containing protein.	Synaptotagmin 3.	0.851
CTU1	THRSP	ENSCAFP00000004252	ENSCAFP00000007232	ATP_bind_3 domain-containing protein.	Thyroid hormone responsive.	0.573
CTU1	ZNF613	ENSCAFP00000004252	ENSCAFP00000037918	ATP_bind_3 domain-containing protein.	Zinc finger protein 613.	0.560
ELOVL6	FASN	ENSCAFP00000016975	ENSCAFP00000009039	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Fatty acid synthase.	0.853
ELOVL6	MID1IP1	ENSCAFP00000016975	ENSCAFP00000034095	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	MID1 interacting protein 1.	0.448
ELOVL6	THRSP	ENSCAFP00000016975	ENSCAFP00000007232	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	Thyroid hormone responsive.	0.668
FASN	ELOVL6	ENSCAFP00000009039	ENSCAFP00000016975	Fatty acid synthase.	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	0.853
FASN	PCK1	ENSCAFP00000009039	ENSCAFP00000046431	Fatty acid synthase.	Phosphoenolpyruvate carboxykinase 1.	0.594
FASN	PLIN1	ENSCAFP00000009039	ENSCAFP00000017642	Fatty acid synthase.	Perilipin; Belongs to the perilipin family.	0.692
FASN	THRSP	ENSCAFP00000009039	ENSCAFP00000007232	Fatty acid synthase.	Thyroid hormone responsive.	0.830
MID1IP1	ELOVL6	ENSCAFP00000034095	ENSCAFP00000016975	MID1 interacting protein 1.	Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]	0.448
MID1IP1	THRSP	ENSCAFP00000034095	ENSCAFP00000007232	MID1 interacting protein 1.	Thyroid hormone responsive.	0.916
PCCA	THRSP	ENSCAFP00000008753	ENSCAFP00000007232	Propionyl-CoA carboxylase subunit alpha.	Thyroid hormone responsive.	0.592
PCK1	FASN	ENSCAFP00000046431	ENSCAFP00000009039	Phosphoenolpyruvate carboxykinase 1.	Fatty acid synthase.	0.594
PCK1	THRSP	ENSCAFP00000046431	ENSCAFP00000007232	Phosphoenolpyruvate carboxykinase 1.	Thyroid hormone responsive.	0.606
PLIN1	FASN	ENSCAFP00000017642	ENSCAFP00000009039	Perilipin; Belongs to the perilipin family.	Fatty acid synthase.	0.692
PLIN1	THRSP	ENSCAFP00000017642	ENSCAFP00000007232	Perilipin; Belongs to the perilipin family.	Thyroid hormone responsive.	0.562
SYT3	CTU1	ENSCAFP00000004392	ENSCAFP00000004252	Synaptotagmin 3.	ATP_bind_3 domain-containing protein.	0.851
SYT3	THRSP	ENSCAFP00000004392	ENSCAFP00000007232	Synaptotagmin 3.	Thyroid hormone responsive.	0.576