RECQL5 protein (Canis lupus familiaris) - STRING interaction network

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Score

RECQL5

ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa)

Predicted Functional Partners:

RPRD1B

0.978

POLR2G

0.973

FANCM

0.950

POLR2A

0.934

POLR2D

0.921

FBH1

0.905

RPRD1A

0.898

RMI1

0.889

TOP3A

0.889

RAD51

0.879

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FANCM	FBH1	ENSCAFP00000041513	ENSCAFP00000007801	FA complementation group M.	F-box DNA helicase 1.	0.935
FANCM	RAD51	ENSCAFP00000041513	ENSCAFP00000058998	FA complementation group M.	DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR [...]	0.961
FANCM	RECQL5	ENSCAFP00000041513	ENSCAFP00000007269	FA complementation group M.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.950
FANCM	RMI1	ENSCAFP00000041513	ENSCAFP00000001985	FA complementation group M.	RecQ mediated genome instability 1.	0.997
FANCM	TOP3A	ENSCAFP00000041513	ENSCAFP00000026983	FA complementation group M.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.996
FBH1	FANCM	ENSCAFP00000007801	ENSCAFP00000041513	F-box DNA helicase 1.	FA complementation group M.	0.935
FBH1	RAD51	ENSCAFP00000007801	ENSCAFP00000058998	F-box DNA helicase 1.	DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR [...]	0.901
FBH1	RECQL5	ENSCAFP00000007801	ENSCAFP00000007269	F-box DNA helicase 1.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.905
FBH1	RMI1	ENSCAFP00000007801	ENSCAFP00000001985	F-box DNA helicase 1.	RecQ mediated genome instability 1.	0.676
FBH1	TOP3A	ENSCAFP00000007801	ENSCAFP00000026983	F-box DNA helicase 1.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.857
POLR2A	POLR2D	ENSCAFP00000037353	ENSCAFP00000061727	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit D.	0.996
POLR2A	POLR2G	ENSCAFP00000037353	ENSCAFP00000022766	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase II subunit G.	0.999
POLR2A	RECQL5	ENSCAFP00000037353	ENSCAFP00000007269	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.934
POLR2A	RPRD1A	ENSCAFP00000037353	ENSCAFP00000026368	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Regulation of nuclear pre-mRNA domain containing 1A.	0.867
POLR2A	RPRD1B	ENSCAFP00000037353	ENSCAFP00000012989	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Regulation of nuclear pre-mRNA domain containing 1B.	0.970
POLR2D	POLR2A	ENSCAFP00000061727	ENSCAFP00000037353	RNA polymerase II subunit D.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.996
POLR2D	POLR2G	ENSCAFP00000061727	ENSCAFP00000022766	RNA polymerase II subunit D.	RNA polymerase II subunit G.	0.998
POLR2D	RECQL5	ENSCAFP00000061727	ENSCAFP00000007269	RNA polymerase II subunit D.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.921
POLR2D	RPRD1A	ENSCAFP00000061727	ENSCAFP00000026368	RNA polymerase II subunit D.	Regulation of nuclear pre-mRNA domain containing 1A.	0.885
POLR2D	RPRD1B	ENSCAFP00000061727	ENSCAFP00000012989	RNA polymerase II subunit D.	Regulation of nuclear pre-mRNA domain containing 1B.	0.888