Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KRTCAP3Keratinocyte associated protein 3. (240 aa)    
Predicted Functional Partners:
TSPEAR
Thrombospondin type laminin G domain and EAR repeats.
      
 0.808
KIF16B
Kinesin family member 16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.755
GPRC5A
G protein-coupled receptor class C group 5 member A.
      
 0.742
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
      
 0.722
PTPN3
Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.
      
 0.696
RAB25
Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
   
  
 0.626
NBEA
Neurobeachin.
      
 0.625
SH3BP5L
SH3 binding domain protein 5 like.
      
 0.598
EPHA5
EPH receptor A5.
      
 0.597
KRT82
Keratin 82; Belongs to the intermediate filament family.
      
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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