STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)    
Predicted Functional Partners:
MAPK12
Mitogen-activated protein kinase.
    
 0.794
ABHD15
Abhydrolase domain containing 15.
      
 0.791
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
    
 
 0.779
KLHL29
Kelch like family member 29.
      
 0.690
PTS
6-pyruvoyltetrahydropterin synthase.
    
 
 0.584
ADAM17
Uncharacterized protein.
   
 
 0.572
NFE2L3
Nuclear factor, erythroid 2 like 3.
      
 0.556
RALB
RAS like proto-oncogene B.
   
 
 0.552
SLC16A7
Solute carrier family 16 member 7.
   
  
 0.552
TMEM185A
Transmembrane protein 185A.
    
 
 0.531
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.