STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (186 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
    
 0.925
TSC1
TSC complex subunit 1.
    
 0.849
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.827
FAM174B
Uncharacterized protein.
      
 0.810
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.787
TBC1D7
TBC1 domain family member 7.
     
 0.770
AKT1S1
AKT1 substrate 1.
    
 0.750
MLST8
MTOR associated protein, LST8 homolog.
    
 0.742
BNIP3
BCL2 interacting protein 3.
    
 0.728
THAP1
THAP domain containing 1.
    
 
 0.693
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.