STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAND2Cullin associated and neddylation dissociated 2 (putative). (1383 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 
 0.853
CUL1
Cullin 1; Belongs to the cullin family.
   
 
 0.848
CUL5
Cullin 5; Belongs to the cullin family.
   
 
 0.818
RBX1
Ring-box 1.
    
 
 0.817
CUL2
Cullin 2; Belongs to the cullin family.
    
 
 0.808
KLHL12
Adiponectin receptor 1.
      
 0.758
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
   
 
 0.704
UBE2M
Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.698
CNOT2
CCR4-NOT transcription complex subunit 2.
   
  
 0.689
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 
 0.644
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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