STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMAC2Distal membrane arm assembly complex 2. (257 aa)    
Predicted Functional Partners:
AASS
Aminoadipate-semialdehyde synthase.
      
 0.733
ATP5PB
ATP synthase peripheral stalk-membrane subunit b.
    
 
 0.728
SLC25A12
Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.712
FOXRED1
FAD dependent oxidoreductase domain containing 1.
   
  
 0.687
ACBD3
Acyl-CoA binding domain containing 3.
   
  
 0.683
AASDH
Aminoadipate-semialdehyde dehydrogenase.
      
 0.605
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.
      
 0.599
DMAC1
Distal membrane arm assembly complex 1.
   
  
 0.575
GPR183
G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family.
      
 0.561
SDHC
Succinate dehydrogenase complex subunit C.
   
  
 0.558
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.