STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR39G protein-coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (429 aa)    
Predicted Functional Partners:
GHRL
Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family.
   
 
 0.723
MLN
Motilin; Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle; Belongs to the motilin family.
   
  
 0.711
ABHD15
Abhydrolase domain containing 15.
   
  
 0.700
GPR37L1
G protein-coupled receptor 37 like 1.
   
  
 0.613
ANKS4B
Ankyrin repeat and sterile alpha motif domain containing 4B.
   
 
 0.606
TRPM7
Transient receptor potential cation channel subfamily M member 7.
   
  
 0.580
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
   
 0.570
GNA14
G protein subunit alpha 14.
   
 0.570
MBOAT4
Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family.
    
 
 0.570
GPR68
G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family.
     
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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