STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LYPD1LY6/PLAUR domain containing 1. (141 aa)    
Predicted Functional Partners:
ALKBH5
AlkB homolog 5, RNA demethylase.
      
 0.591
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
    
 
 0.589
NXPH1
Neurexophilin; May be signaling molecules that resemble neuropeptides.
      
 0.580
CALB1
Calbindin 1.
   
  
 0.551
ECEL1
Endothelin converting enzyme like 1.
    
 
 0.529
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
    
 
 0.501
IGF2BP2
Insulin like growth factor 2 mRNA binding protein 2.
      
 0.483
NDNF
Neuron derived neurotrophic factor.
      
 0.466
CACNA1G
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
      
 0.466
MKRN2
Makorin ring finger protein 2.
      
 0.464
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.