STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EVPLEnvoplakin. (2072 aa)    
Predicted Functional Partners:
PPL
Periplakin.
  
0.964
CSTA
Cystatin A; Belongs to the cystatin family.
   
 0.796
LOC100855871
Uncharacterized protein.
    
 
 0.792
PKP1
Uncharacterized protein.
   
 
 0.789
CDSN
Corneodesmosin.
   
 
 0.784
TGM1
Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family.
   
 
 0.772
JUP
Uncharacterized protein.
   
 
 0.734
A2ML1
Alpha-2-macroglobulin like 1.
   
  
 0.698
TMEM79
Transmembrane protein 79.
   
  
 0.682
DSG2
Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).
   
 
 0.626
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.