GALR2 protein (Canis lupus familiaris) - STRING interaction network

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GALR2

Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (386 aa)

Predicted Functional Partners:

GAL

0.996

GALR1

0.926

GALR3

0.907

SPX

0.729

TMEM8A

0.647

SST

0.640

POMC

0.605

MCHR1

0.599

SSTR1

0.579

SSTR3

0.578

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAL	GALR1	ENSCAFP00000015855	ENSCAFP00000000020	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.999
GAL	GALR2	ENSCAFP00000015855	ENSCAFP00000007485	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.996
GAL	GALR3	ENSCAFP00000015855	ENSCAFP00000002089	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.995
GAL	MCHR1	ENSCAFP00000015855	ENSCAFP00000030916	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Melanin concentrating hormone receptor 1.	0.678
GAL	POMC	ENSCAFP00000015855	ENSCAFP00000006163	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Proopiomelanocortin.	0.726
GAL	SPX	ENSCAFP00000015855	ENSCAFP00000018049	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Spexin hormone.	0.614
GAL	SST	ENSCAFP00000015855	ENSCAFP00000064277	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.	0.943
GAL	SSTR1	ENSCAFP00000015855	ENSCAFP00000020273	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Somatostatin receptor type 1; Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins (By similarity).	0.663
GAL	SSTR3	ENSCAFP00000015855	ENSCAFP00000037746	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Somatostatin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.597
GALR1	GAL	ENSCAFP00000000020	ENSCAFP00000015855	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	0.999
GALR1	GALR2	ENSCAFP00000000020	ENSCAFP00000007485	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.926
GALR1	GALR3	ENSCAFP00000000020	ENSCAFP00000002089	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.927
GALR1	MCHR1	ENSCAFP00000000020	ENSCAFP00000030916	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Melanin concentrating hormone receptor 1.	0.536
GALR1	POMC	ENSCAFP00000000020	ENSCAFP00000006163	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Proopiomelanocortin.	0.626
GALR1	SPX	ENSCAFP00000000020	ENSCAFP00000018049	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Spexin hormone.	0.498
GALR1	SST	ENSCAFP00000000020	ENSCAFP00000064277	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.	0.676
GALR1	SSTR1	ENSCAFP00000000020	ENSCAFP00000020273	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Somatostatin receptor type 1; Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins (By similarity).	0.591
GALR1	SSTR3	ENSCAFP00000000020	ENSCAFP00000037746	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Somatostatin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family.	0.549
GALR2	GAL	ENSCAFP00000007485	ENSCAFP00000015855	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	0.996
GALR2	GALR1	ENSCAFP00000007485	ENSCAFP00000000020	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.926