Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZACNZinc-activated ligand-gated ion channel; Zinc-activated ligand-gated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (410 aa)    
Predicted Functional Partners:
SLC26A9
Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.624
IARS2
Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.592
TXNDC12
Thioredoxin domain containing 12.
      
 0.591
C9H17orf58
Chromosome 9 C17orf58 homolog.
      
 0.581
CYBC1
Cytochrome b-245 chaperone 1.
      
 0.524
ENSCAFP00000043977
Uncharacterized protein.
      
 0.524
ABLIM3
Actin binding LIM protein family member 3.
      
 0.517
AQP5
Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.515
SLC43A1
Large neutral amino acids transporter small subunit 3.
    
   0.508
SLC41A3
Solute carrier family 41 member 3.
    
 
 0.486
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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