KLF5 protein (Canis lupus familiaris) - STRING interaction network

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Score

KLF5

Kruppel like factor 5. (457 aa)

Predicted Functional Partners:

WWP1

0.945

FBXW7

0.940

EP300

0.866

PIBF1

0.758

FBXW9

0.729

WWP2

0.715

ESRRB

0.713

CTNNB1

0.702

CREBBP

0.667

SMURF2

0.663

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	CTNNB1	ENSCAFP00000036447	ENSCAFP00000007783	CREB binding protein.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.995
CREBBP	EP300	ENSCAFP00000036447	ENSCAFP00000001585	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	KLF5	ENSCAFP00000036447	ENSCAFP00000007496	CREB binding protein.	Kruppel like factor 5.	0.667
CTNNB1	CREBBP	ENSCAFP00000007783	ENSCAFP00000036447	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	CREB binding protein.	0.995
CTNNB1	EP300	ENSCAFP00000007783	ENSCAFP00000001585	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	E1A binding protein p300.	0.994
CTNNB1	FBXW7	ENSCAFP00000007783	ENSCAFP00000011996	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	F-box and WD repeat domain containing 7.	0.874
CTNNB1	FBXW9	ENSCAFP00000007783	ENSCAFP00000025388	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	F-box and WD repeat domain containing 9.	0.613
CTNNB1	KLF5	ENSCAFP00000007783	ENSCAFP00000007496	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	Kruppel like factor 5.	0.702
EP300	CREBBP	ENSCAFP00000001585	ENSCAFP00000036447	E1A binding protein p300.	CREB binding protein.	0.999
EP300	CTNNB1	ENSCAFP00000001585	ENSCAFP00000007783	E1A binding protein p300.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.994
EP300	KLF5	ENSCAFP00000001585	ENSCAFP00000007496	E1A binding protein p300.	Kruppel like factor 5.	0.866
ESRRB	KLF5	ENSCAFP00000050405	ENSCAFP00000007496	Estrogen related receptor beta.	Kruppel like factor 5.	0.713
FBXW7	CTNNB1	ENSCAFP00000011996	ENSCAFP00000007783	F-box and WD repeat domain containing 7.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.874
FBXW7	KLF5	ENSCAFP00000011996	ENSCAFP00000007496	F-box and WD repeat domain containing 7.	Kruppel like factor 5.	0.940
FBXW9	CTNNB1	ENSCAFP00000025388	ENSCAFP00000007783	F-box and WD repeat domain containing 9.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.613
FBXW9	KLF5	ENSCAFP00000025388	ENSCAFP00000007496	F-box and WD repeat domain containing 9.	Kruppel like factor 5.	0.729
KLF5	CREBBP	ENSCAFP00000007496	ENSCAFP00000036447	Kruppel like factor 5.	CREB binding protein.	0.667
KLF5	CTNNB1	ENSCAFP00000007496	ENSCAFP00000007783	Kruppel like factor 5.	Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...]	0.702
KLF5	EP300	ENSCAFP00000007496	ENSCAFP00000001585	Kruppel like factor 5.	E1A binding protein p300.	0.866
KLF5	ESRRB	ENSCAFP00000007496	ENSCAFP00000050405	Kruppel like factor 5.	Estrogen related receptor beta.	0.713