RNF157 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RNF157

Ring finger protein 157. (716 aa)

Predicted Functional Partners:

UNC45B

0.672

MEGF8

0.641

ATRN

0.641

ATRNL1

0.641

PRPSAP1

0.585

HDAC1

0.583

HDAC2

0.583

FXR2

0.581

CHD1

0.573

SAMD3

0.532

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATRN	RNF157	ENSCAFP00000009513	ENSCAFP00000007536	Attractin.	Ring finger protein 157.	0.641
ATRNL1	MEGF8	ENSCAFP00000017303	ENSCAFP00000007208	Attractin like 1.	Multiple EGF like domains 8.	0.407
ATRNL1	RNF157	ENSCAFP00000017303	ENSCAFP00000007536	Attractin like 1.	Ring finger protein 157.	0.641
CHD1	RNF157	ENSCAFP00000011432	ENSCAFP00000007536	Chromodomain helicase DNA binding protein 1.	Ring finger protein 157.	0.573
FXR2	RNF157	ENSCAFP00000052542	ENSCAFP00000007536	FMR1 autosomal homolog 2.	Ring finger protein 157.	0.581
HDAC1	HDAC2	ENSCAFP00000036819	ENSCAFP00000042408	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.980
HDAC1	RNF157	ENSCAFP00000036819	ENSCAFP00000007536	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Ring finger protein 157.	0.583
HDAC2	HDAC1	ENSCAFP00000042408	ENSCAFP00000036819	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.980
HDAC2	RNF157	ENSCAFP00000042408	ENSCAFP00000007536	Histone deacetylase 2.	Ring finger protein 157.	0.583
MEGF8	ATRNL1	ENSCAFP00000007208	ENSCAFP00000017303	Multiple EGF like domains 8.	Attractin like 1.	0.407
MEGF8	RNF157	ENSCAFP00000007208	ENSCAFP00000007536	Multiple EGF like domains 8.	Ring finger protein 157.	0.641
PRPSAP1	RNF157	ENSCAFP00000037092	ENSCAFP00000007536	Phosphoribosyl pyrophosphate synthetase associated protein 1.	Ring finger protein 157.	0.585
RNF157	ATRN	ENSCAFP00000007536	ENSCAFP00000009513	Ring finger protein 157.	Attractin.	0.641
RNF157	ATRNL1	ENSCAFP00000007536	ENSCAFP00000017303	Ring finger protein 157.	Attractin like 1.	0.641
RNF157	CHD1	ENSCAFP00000007536	ENSCAFP00000011432	Ring finger protein 157.	Chromodomain helicase DNA binding protein 1.	0.573
RNF157	FXR2	ENSCAFP00000007536	ENSCAFP00000052542	Ring finger protein 157.	FMR1 autosomal homolog 2.	0.581
RNF157	HDAC1	ENSCAFP00000007536	ENSCAFP00000036819	Ring finger protein 157.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.583
RNF157	HDAC2	ENSCAFP00000007536	ENSCAFP00000042408	Ring finger protein 157.	Histone deacetylase 2.	0.583
RNF157	MEGF8	ENSCAFP00000007536	ENSCAFP00000007208	Ring finger protein 157.	Multiple EGF like domains 8.	0.641
RNF157	PRPSAP1	ENSCAFP00000007536	ENSCAFP00000037092	Ring finger protein 157.	Phosphoribosyl pyrophosphate synthetase associated protein 1.	0.585