STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF157Ring finger protein 157. (716 aa)    
Predicted Functional Partners:
MEGF8
Multiple EGF like domains 8.
   
 
 0.724
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
   
  
 0.678
ATRN
Attractin.
   
 
 0.624
MOSMO
Modulator of smoothened.
   
  
 0.593
ATRNL1
Attractin like 1.
   
 
 0.576
GPR62
G protein-coupled receptor 62.
   
 
 0.536
GPR61
G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.530
OTOP3
Otopetrin 3.
      
 0.503
CDH12
Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.499
FAM13A
Family with sequence similarity 13 member A.
   
  
 0.487
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.