STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCTD12Potassium channel tetramerization domain containing 12. (348 aa)    
Predicted Functional Partners:
EXOC7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.811
DGKI
Diacylglycerol kinase.
   
  
 0.719
GABRA4
Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.599
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
    
 
 0.598
UNC13B
Uncharacterized protein.
      
 0.592
CLIC4
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.533
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
      
 0.533
SLC6A4
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.520
TLX3
T cell leukemia homeobox 3.
      
 0.517
SOHLH1
Spermatogenesis and oogenesis specific basic helix-loop-helix 1.
   
   0.501
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.