STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (491 aa)    
Predicted Functional Partners:
CYP2S1
Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family.
  
  
 
0.829
EPHX1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
   
 0.804
CYP2C18
Cytochrome P450 2C21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Showed testosterone hydrolase activity.
     
  0.796
CYP7A1
Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
 0.760
CYP26B1
Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.
  
0.743
LOC479911
Glutathione S-transferase.
   
 
 0.724
LOC479912
Uncharacterized protein; Belongs to the GST superfamily.
   
 
 0.724
GSTO1
Glutathione S-transferase omega 1; Belongs to the GST superfamily.
    
 0.723
LOC484492
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
  0.718
CYP2J2
Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family.
  
 
 
0.708
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.