STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITIH2Inter-alpha-trypsin inhibitor heavy chain 2. (946 aa)    
Predicted Functional Partners:
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
  
 
0.918
APOH
Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
   
 0.894
APOB
Apolipoprotein B.
   
  
 0.881
AMBP
Alpha-1-microglobulin/bikunin precursor.
   
 
 0.865
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
   
 0.851
ITIH3
Inter-alpha-trypsin inhibitor heavy chain 3.
  
  
0.849
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
   
  
 0.815
AHSG
Alpha 2-HS glycoprotein.
   
 0.810
MAPT
Microtubule-associated protein.
    
 0.788
C5
Complement C5.
   
 
 0.777
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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