STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC485601Uncharacterized protein; Belongs to the peptidase C14A family. (368 aa)    
Predicted Functional Partners:
GPR33
G protein-coupled receptor 33.
      
 0.789
CCL27
Cutaneous T cell attracting chemokine.
      
 0.677
CENPN
Centromere protein N.
   
 
 0.651
TGM5
Transglutaminase 5.
   
  
 0.646
CENPI
Centromere protein I.
   
 
 0.620
CENPP
Centromere protein P.
   
 
 0.618
XIAP
Baculoviral IAP-repeat containing protein 4.
   
 
 0.611
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).
   
 
 0.610
CCDC105
Coiled-coil domain containing 105.
   
 
 0.609
CENPQ
Centromere protein Q.
   
 
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.