| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMPD2 | ENPP1 | ENSCAFP00000031117 | ENSCAFP00000000001 | Adenosine monophosphate deaminase 2. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.915 |
| AMPD2 | ENPP3 | ENSCAFP00000031117 | ENSCAFP00000000528 | Adenosine monophosphate deaminase 2. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.917 |
| AMPD2 | ENTPD3 | ENSCAFP00000031117 | ENSCAFP00000007656 | Adenosine monophosphate deaminase 2. | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. | 0.919 |
| AMPD2 | ENTPD5 | ENSCAFP00000031117 | ENSCAFP00000041007 | Adenosine monophosphate deaminase 2. | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. | 0.913 |
| AMPD2 | ENTPD6 | ENSCAFP00000031117 | ENSCAFP00000045638 | Adenosine monophosphate deaminase 2. | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 0.921 |
| CMPK1 | CTPS1 | ENSCAFP00000047166 | ENSCAFP00000004062 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.407 |
| CMPK1 | CTPS2 | ENSCAFP00000047166 | ENSCAFP00000049397 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.407 |
| CMPK1 | ENPP1 | ENSCAFP00000047166 | ENSCAFP00000000001 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.902 |
| CMPK1 | ENPP3 | ENSCAFP00000047166 | ENSCAFP00000000528 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.906 |
| CMPK1 | ENTPD3 | ENSCAFP00000047166 | ENSCAFP00000007656 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. | 0.926 |
| CMPK1 | NME7 | ENSCAFP00000047166 | ENSCAFP00000022471 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.944 |
| CMPK1 | RRM1 | ENSCAFP00000047166 | ENSCAFP00000008963 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.952 |
| CTPS1 | CMPK1 | ENSCAFP00000004062 | ENSCAFP00000047166 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.407 |
| CTPS1 | CTPS2 | ENSCAFP00000004062 | ENSCAFP00000049397 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.956 |
| CTPS1 | ENPP1 | ENSCAFP00000004062 | ENSCAFP00000000001 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase 1. | 0.927 |
| CTPS1 | ENPP3 | ENSCAFP00000004062 | ENSCAFP00000000528 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleotide pyrophosphatase/phosphodiesterase 3. | 0.907 |
| CTPS1 | ENTPD3 | ENSCAFP00000004062 | ENSCAFP00000007656 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. | 0.923 |
| CTPS1 | NME7 | ENSCAFP00000004062 | ENSCAFP00000022471 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase 7; Belongs to the NDK family. | 0.938 |
| CTPS1 | RRM1 | ENSCAFP00000004062 | ENSCAFP00000008963 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.452 |
| CTPS2 | CMPK1 | ENSCAFP00000049397 | ENSCAFP00000047166 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.407 |