STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
METTL23Uncharacterized protein. (362 aa)    
Predicted Functional Partners:
PRMT7
Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...]
   
 
 0.694
METTL22
Methyltransferase like 22.
   
 
 0.672
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
   
  
 0.661
EEF1AKMT2
Methyltranfer_dom domain-containing protein.
   
  
 0.613
METTL18
Methyltransferase like 18.
   
  
 0.605
PRMT1
Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
   
 
 0.578
AANAT
Arylalkylamine N-acetyltransferase.
   
 
 0.568
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.562
MFSD11
Major facilitator superfamily domain containing 11.
      
 0.538
CAMKMT
Calmodulin-lysine N-methyltransferase.
      
 0.526
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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