STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL23Uncharacterized protein. (362 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
   
  
 0.789
METTL18
Methyltransferase like 18.
   
  
 0.723
GABPA
GA binding protein transcription factor subunit alpha.
      
 0.687
MFSD11
Major facilitator superfamily domain containing 11.
      
 0.679
SEC14L1
SEC14 like lipid binding 1.
      
 0.679
AANAT
Arylalkylamine N-acetyltransferase.
   
  
 0.677
PRMT7
Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...]
   
 
 0.629
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.612
TMEM8A
Transmembrane protein 8A.
      
 0.602
METTL22
Methyltransferase like 22.
   
 
0.581
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.