MNX1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MNX1

Motor neuron and pancreas homeobox 1. (202 aa)

Predicted Functional Partners:

RFX6

0.644

FAM131B

0.628

VIPR1

0.616

TSPAN2

0.598

DFFB

0.592

TBX20

0.586

POU3F1

0.585

GLIS3

0.569

POU3F3

0.565

POU1F1

0.543

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DFFB	MNX1	ENSCAFP00000058291	ENSCAFP00000007681	DNA fragmentation factor subunit beta.	Motor neuron and pancreas homeobox 1.	0.592
FAM131B	MNX1	ENSCAFP00000035327	ENSCAFP00000007681	Family with sequence similarity 131 member B.	Motor neuron and pancreas homeobox 1.	0.628
GLIS3	MNX1	ENSCAFP00000041683	ENSCAFP00000007681	GLIS family zinc finger 3.	Motor neuron and pancreas homeobox 1.	0.569
GLIS3	RFX6	ENSCAFP00000041683	ENSCAFP00000001307	GLIS family zinc finger 3.	Regulatory factor X6.	0.722
MNX1	DFFB	ENSCAFP00000007681	ENSCAFP00000058291	Motor neuron and pancreas homeobox 1.	DNA fragmentation factor subunit beta.	0.592
MNX1	FAM131B	ENSCAFP00000007681	ENSCAFP00000035327	Motor neuron and pancreas homeobox 1.	Family with sequence similarity 131 member B.	0.628
MNX1	GLIS3	ENSCAFP00000007681	ENSCAFP00000041683	Motor neuron and pancreas homeobox 1.	GLIS family zinc finger 3.	0.569
MNX1	POU1F1	ENSCAFP00000007681	ENSCAFP00000011512	Motor neuron and pancreas homeobox 1.	Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.	0.543
MNX1	POU3F1	ENSCAFP00000007681	ENSCAFP00000033065	Motor neuron and pancreas homeobox 1.	POU domain protein.	0.585
MNX1	POU3F3	ENSCAFP00000007681	ENSCAFP00000005157	Motor neuron and pancreas homeobox 1.	POU domain protein.	0.565
MNX1	RFX6	ENSCAFP00000007681	ENSCAFP00000001307	Motor neuron and pancreas homeobox 1.	Regulatory factor X6.	0.644
MNX1	TBX20	ENSCAFP00000007681	ENSCAFP00000036063	Motor neuron and pancreas homeobox 1.	T-box transcription factor 20.	0.586
MNX1	TSPAN2	ENSCAFP00000007681	ENSCAFP00000063025	Motor neuron and pancreas homeobox 1.	Tetraspanin.	0.598
MNX1	VIPR1	ENSCAFP00000007681	ENSCAFP00000007864	Motor neuron and pancreas homeobox 1.	Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.616
POU1F1	MNX1	ENSCAFP00000011512	ENSCAFP00000007681	Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.	Motor neuron and pancreas homeobox 1.	0.543
POU3F1	MNX1	ENSCAFP00000033065	ENSCAFP00000007681	POU domain protein.	Motor neuron and pancreas homeobox 1.	0.585
POU3F3	MNX1	ENSCAFP00000005157	ENSCAFP00000007681	POU domain protein.	Motor neuron and pancreas homeobox 1.	0.565
RFX6	GLIS3	ENSCAFP00000001307	ENSCAFP00000041683	Regulatory factor X6.	GLIS family zinc finger 3.	0.722
RFX6	MNX1	ENSCAFP00000001307	ENSCAFP00000007681	Regulatory factor X6.	Motor neuron and pancreas homeobox 1.	0.644
TBX20	MNX1	ENSCAFP00000036063	ENSCAFP00000007681	T-box transcription factor 20.	Motor neuron and pancreas homeobox 1.	0.586