STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MNX1Motor neuron and pancreas homeobox 1. (202 aa)    
Predicted Functional Partners:
RFX6
Regulatory factor X6.
      
 0.708
FAM131B
Family with sequence similarity 131 member B.
   
  
 0.659
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
  
 0.651
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
      
 0.638
ZIC4
Zic family member 4.
    
 
 0.598
FOXA2
Forkhead box A2.
    
 
 0.580
POU3F1
POU domain protein.
  
 
 
 0.570
DFFB
DNA fragmentation factor subunit beta.
      
 0.567
LHX3
LIM homeobox 3.
   
 
 0.541
ONECUT1
One cut domain family member.
      
 0.524
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.