FOXA2 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

FOXA2

Forkhead box A2. (468 aa)

Predicted Functional Partners:

OTX2

0.936

RPS6KB2

0.889

SOX17

0.854

GATA4

0.818

RPS6KB1

0.785

ENSCAFP00000049628

0.785

SHH

0.777

EOMES

0.764

BMP4

0.755

PITX3

0.751

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	EOMES	ENSCAFP00000021935	ENSCAFP00000042151	TGF_BETA_2 domain-containing protein.	Eomesodermin.	0.647
BMP4	FOXA2	ENSCAFP00000021935	ENSCAFP00000007716	TGF_BETA_2 domain-containing protein.	Forkhead box A2.	0.755
BMP4	GATA4	ENSCAFP00000021935	ENSCAFP00000038219	TGF_BETA_2 domain-containing protein.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.557
BMP4	OTX2	ENSCAFP00000021935	ENSCAFP00000022423	TGF_BETA_2 domain-containing protein.	Orthodenticle homeobox 2.	0.458
BMP4	SHH	ENSCAFP00000021935	ENSCAFP00000050657	TGF_BETA_2 domain-containing protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.884
BMP4	SOX17	ENSCAFP00000021935	ENSCAFP00000037797	TGF_BETA_2 domain-containing protein.	SRY-box 17.	0.824
ENSCAFP00000049628	FOXA2	ENSCAFP00000049628	ENSCAFP00000007716	AGC-kinase C-terminal domain-containing protein.	Forkhead box A2.	0.785
ENSCAFP00000049628	RPS6KB2	ENSCAFP00000049628	ENSCAFP00000036722	AGC-kinase C-terminal domain-containing protein.	Non-specific serine/threonine protein kinase.	0.799
EOMES	BMP4	ENSCAFP00000042151	ENSCAFP00000021935	Eomesodermin.	TGF_BETA_2 domain-containing protein.	0.647
EOMES	FOXA2	ENSCAFP00000042151	ENSCAFP00000007716	Eomesodermin.	Forkhead box A2.	0.764
EOMES	GATA4	ENSCAFP00000042151	ENSCAFP00000038219	Eomesodermin.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.504
EOMES	OTX2	ENSCAFP00000042151	ENSCAFP00000022423	Eomesodermin.	Orthodenticle homeobox 2.	0.640
EOMES	SOX17	ENSCAFP00000042151	ENSCAFP00000037797	Eomesodermin.	SRY-box 17.	0.800
FOXA2	BMP4	ENSCAFP00000007716	ENSCAFP00000021935	Forkhead box A2.	TGF_BETA_2 domain-containing protein.	0.755
FOXA2	ENSCAFP00000049628	ENSCAFP00000007716	ENSCAFP00000049628	Forkhead box A2.	AGC-kinase C-terminal domain-containing protein.	0.785
FOXA2	EOMES	ENSCAFP00000007716	ENSCAFP00000042151	Forkhead box A2.	Eomesodermin.	0.764
FOXA2	GATA4	ENSCAFP00000007716	ENSCAFP00000038219	Forkhead box A2.	Transcription factor GATA-4; Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes [...]	0.818
FOXA2	OTX2	ENSCAFP00000007716	ENSCAFP00000022423	Forkhead box A2.	Orthodenticle homeobox 2.	0.936
FOXA2	PITX3	ENSCAFP00000007716	ENSCAFP00000042514	Forkhead box A2.	Homeobox protein.	0.751
FOXA2	RPS6KB1	ENSCAFP00000007716	ENSCAFP00000026092	Forkhead box A2.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.785