STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRRT3Proline rich transmembrane protein 3. (989 aa)    
Predicted Functional Partners:
SPRTN
SprT-like N-terminal domain.
      
 0.783
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
   
  
 0.717
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.713
ZMPSTE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
      
 0.605
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
   
 
 0.599
DKC1
Dyskerin pseudouridine synthase 1.
   
  
 0.598
POLD1
DNA polymerase.
   
  
 0.575
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
      
 0.569
ZZEF1
Zinc finger ZZ-type and EF-hand domain containing 1.
   
  
 0.564
RPS27A
Ubiquitin-like domain-containing protein.
    
 
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.