STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRRT3Proline rich transmembrane protein 3. (989 aa)    
Predicted Functional Partners:
POLR3A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.776
SPRTN
SprT-like N-terminal domain.
      
 0.747
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
   
  
 0.725
DKC1
Dyskerin pseudouridine synthase 1.
   
  
 0.616
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
   
 
 0.613
ZMPSTE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
      
 0.609
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
  
 0.606
POLD1
DNA polymerase.
   
  
 0.598
VSTM2L
V-set and transmembrane domain containing 2 like.
   
  
 0.557
XPA
XPA, DNA damage recognition and repair factor.
   
  
 0.542
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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