STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLB1Phospholipase B1. (1457 aa)    
Predicted Functional Partners:
LYPLA2
PITH domain containing 1.
     
 0.946
LPCAT3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
   
 
 0.936
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
    
 0.935
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.927
MCOLN1
Patatin like phospholipase domain containing 6.
   
 
 0.911
PNPLA7
Patatin like phospholipase domain containing 7.
   
 
 0.911
PLA2G15
Group XV phospholipase A2; Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid. Has high activity with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), catalyzing the transfer of oleic acid to N-acetyl-sphingosine. Required for normal phospholipid degradation in alveolar and peritoneal macrophages and in spleen (By similarity).
     
 0.910
CYP2J2
Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family.
   
 
 0.905
PLAAT3
Phospholipase A and acyltransferase 3.
     
 0.905
TMEM86B
Transmembrane protein 86B.
   
 
  0.902
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.