STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASB13Ankyrin repeat and SOCS box containing 13. (263 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
    
 
 0.809
LOC491503
ANK_REP_REGION domain-containing protein.
  
 
  0.553
ANKRD54
Ankyrin repeat domain 54.
  
    0.531
LRRC41
Leucine rich repeat containing 41.
      
 0.526
ASB6
Ankyrin repeat and SOCS box containing 6.
  
 
 
0.526
KLHL42
Kelch like family member 42.
      
 0.516
CDKN2C
Cyclin dependent kinase inhibitor 2C.
  
 
   0.516
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.512
ASB7
Ankyrin repeat and SOCS box containing 7.
  
 
0.510
ELOB
Elongin B.
    
 
 0.494
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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