STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL17REInterleukin 17 receptor E. (668 aa)    
Predicted Functional Partners:
IL17C
Interleukin 17C.
   
 0.982
IL17RA
Interleukin 17 receptor A.
    
 0.931
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
     
 0.910
IL17RD
Interleukin 17 receptor D.
    
 0.874
TRAF3IP2
TRAF3 interacting protein 2.
     
 0.799
ENSCAFP00000053409
SEFIR domain-containing protein.
     
 0.799
IL17F
Interleukin 17F.
     
 0.736
IL17RB
Interleukin 17 receptor B.
      
 0.734
IL17B
Interleukin 17B.
      
 0.669
MKRN2
Makorin ring finger protein 2.
      
 0.568
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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