STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (459 aa)    
Predicted Functional Partners:
VIP
Vasoactive intestinal peptide.
    
 0.996
ADCYAP1
GLUCAGON domain-containing protein.
   
 
 0.916
TMEM86A
Transmembrane protein 86A.
      
 0.738
TSPAN2
Tetraspanin.
      
 0.688
AAAS
Aladin WD repeat nucleoporin.
      
 0.637
SLC51A
Solute carrier family 51 alpha subunit.
   
  
 0.621
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
      
 0.621
GHRH
Growth hormone releasing hormone.
   
 
 0.603
RAMP1
Receptor activity modifying protein 1.
    
 
 0.595
VIPR2
Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family.
  
 
0.577
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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