| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADCYAP1 | GNAS | ENSCAFP00000054542 | ENSCAFP00000041597 | GLUCAGON domain-containing protein. | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | 0.605 |
| ADCYAP1 | GNB2 | ENSCAFP00000054542 | ENSCAFP00000033929 | GLUCAGON domain-containing protein. | G protein subunit beta 2. | 0.519 |
| ADCYAP1 | GNB3 | ENSCAFP00000054542 | ENSCAFP00000058821 | GLUCAGON domain-containing protein. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.468 |
| ADCYAP1 | GNG2 | ENSCAFP00000054542 | ENSCAFP00000042834 | GLUCAGON domain-containing protein. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.592 |
| ADCYAP1 | GNG4 | ENSCAFP00000054542 | ENSCAFP00000037704 | GLUCAGON domain-containing protein. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.596 |
| ADCYAP1 | VIPR1 | ENSCAFP00000054542 | ENSCAFP00000007864 | GLUCAGON domain-containing protein. | Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.959 |
| ADCYAP1 | VIPR2 | ENSCAFP00000054542 | ENSCAFP00000057970 | GLUCAGON domain-containing protein. | Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.984 |
| GNAS | ADCYAP1 | ENSCAFP00000041597 | ENSCAFP00000054542 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | GLUCAGON domain-containing protein. | 0.605 |
| GNAS | GNB2 | ENSCAFP00000041597 | ENSCAFP00000033929 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | G protein subunit beta 2. | 0.992 |
| GNAS | GNB3 | ENSCAFP00000041597 | ENSCAFP00000058821 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.992 |
| GNAS | GNB5 | ENSCAFP00000041597 | ENSCAFP00000023022 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | G protein subunit beta 5. | 0.899 |
| GNAS | GNG2 | ENSCAFP00000041597 | ENSCAFP00000042834 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.996 |
| GNAS | GNG4 | ENSCAFP00000041597 | ENSCAFP00000037704 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.994 |
| GNAS | VIPR1 | ENSCAFP00000041597 | ENSCAFP00000007864 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.894 |
| GNAS | VIPR2 | ENSCAFP00000041597 | ENSCAFP00000057970 | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.824 |
| GNB2 | ADCYAP1 | ENSCAFP00000033929 | ENSCAFP00000054542 | G protein subunit beta 2. | GLUCAGON domain-containing protein. | 0.519 |
| GNB2 | GNAS | ENSCAFP00000033929 | ENSCAFP00000041597 | G protein subunit beta 2. | Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. | 0.992 |
| GNB2 | GNB3 | ENSCAFP00000033929 | ENSCAFP00000058821 | G protein subunit beta 2. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.981 |
| GNB2 | GNB5 | ENSCAFP00000033929 | ENSCAFP00000023022 | G protein subunit beta 2. | G protein subunit beta 5. | 0.715 |
| GNB2 | GNG2 | ENSCAFP00000033929 | ENSCAFP00000042834 | G protein subunit beta 2. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.987 |