STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC22CSEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. (303 aa)    
Predicted Functional Partners:
GOSR2
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
    
 0.930
STX5
Syntaxin 5; Belongs to the syntaxin family.
   
 0.924
BET1
Bet1 golgi vesicular membrane trafficking protein.
   
 0.880
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.871
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
 
 0.853
LOC475497
Uncharacterized protein; Belongs to the synaptobrevin family.
    
 0.834
SEC23A
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 0.820
NAPB
NSF attachment protein beta.
   
 0.818
NAPA
NSF attachment protein alpha.
   
 0.817
SEC24B
SEC24 homolog B, COPII coat complex component.
   
 0.810
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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