STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC8Transmembrane channel-like protein. (702 aa)    
Predicted Functional Partners:
SYNGR2
MARVEL domain-containing protein.
 
    
 0.835
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
   
 
 0.826
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
    
 
 0.671
MYBPC1
Myosin binding protein C, slow type.
    
 0.664
CKMT1A
Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.
      
 0.631
CKM
Creatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family.
      
 0.631
CKMT2
Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family.
      
 0.623
IDUA
Alpha-L-iduronidase.
    
 0.607
CPT2
Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family.
    
 
 0.605
DCAF6
DDB1 and CUL4 associated factor 6.
      
 0.591
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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