TK1 protein (Canis lupus familiaris) - STRING interaction network

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Score

TK1

Thymidine kinase. (242 aa)

Predicted Functional Partners:

TYMS

0.995

CDA

0.988

DCTD

0.986

UPP1-2

0.932

NT5C

0.926

ENSCAFP00000050332

0.923

NT5C3B

0.920

NT5M

0.917

CMPK1

0.917

NT5E

0.914

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDA	DCTD	ENSCAFP00000022181	ENSCAFP00000041962	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	dCMP deaminase.	0.578
CDA	ENSCAFP00000050332	ENSCAFP00000022181	ENSCAFP00000050332	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Thymidylat_synt domain-containing protein.	0.788
CDA	NT5C	ENSCAFP00000022181	ENSCAFP00000035634	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	5', 3'-nucleotidase, cytosolic.	0.907
CDA	NT5C3B	ENSCAFP00000022181	ENSCAFP00000023338	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.927
CDA	NT5E	ENSCAFP00000022181	ENSCAFP00000004456	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.927
CDA	NT5M	ENSCAFP00000022181	ENSCAFP00000041751	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	5',3'-nucleotidase, mitochondrial.	0.903
CDA	TK1	ENSCAFP00000022181	ENSCAFP00000007911	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Thymidine kinase.	0.988
CDA	TYMS	ENSCAFP00000022181	ENSCAFP00000027096	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	Thymidylate synthetase.	0.835
CDA	UPP1-2	ENSCAFP00000022181	ENSCAFP00000057328	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	PNP_UDP_1 domain-containing protein.	0.994
CMPK1	DCTD	ENSCAFP00000047166	ENSCAFP00000041962	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	dCMP deaminase.	0.944
CMPK1	NT5C	ENSCAFP00000047166	ENSCAFP00000035634	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	5', 3'-nucleotidase, cytosolic.	0.950
CMPK1	NT5C3B	ENSCAFP00000047166	ENSCAFP00000023338	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.910
CMPK1	NT5E	ENSCAFP00000047166	ENSCAFP00000004456	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.	0.908
CMPK1	NT5M	ENSCAFP00000047166	ENSCAFP00000041751	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	5',3'-nucleotidase, mitochondrial.	0.943
CMPK1	TK1	ENSCAFP00000047166	ENSCAFP00000007911	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidine kinase.	0.917
DCTD	CDA	ENSCAFP00000041962	ENSCAFP00000022181	dCMP deaminase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.578
DCTD	CMPK1	ENSCAFP00000041962	ENSCAFP00000047166	dCMP deaminase.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.944
DCTD	ENSCAFP00000050332	ENSCAFP00000041962	ENSCAFP00000050332	dCMP deaminase.	Thymidylat_synt domain-containing protein.	0.714
DCTD	NT5C	ENSCAFP00000041962	ENSCAFP00000035634	dCMP deaminase.	5', 3'-nucleotidase, cytosolic.	0.937
DCTD	NT5C3B	ENSCAFP00000041962	ENSCAFP00000023338	dCMP deaminase.	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.	0.918